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Purpose-built for physicians GLP-1s lower BMI, preserve kidney function for adults with diabetes post-kidney transplant Key takeaways: Adults with diabetes who underwent kidney transplantation had greater reductions in BMI and body weight if they used a GLP-1

"The glucagon-like peptide 1 analogue Exendin-4 attenuates the nicotine-induced locomotor stimulation, accumbal dopamine release, conditioned place preference as well as the expression of locomotor sensitization in mice." PloS one 8.10 (2013): e77284

Elevated cAMP in cardiac cells increases both the rate and force of contraction

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In fasted states, the GLP-1 agonist Exendin-4 attenuates glucose-6-phosphatase and maintains glycogen synthase (GYS) activity but has no effect in PASK-deficient mice, whereas they already maintain an elevated level of expression of GYS [142]