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2 Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA

The treatments with MOTS-c, exendin-4 and combination treatment reduced blood glucose levels (scrambled: 331.7 200.98 mg dl 1 , MOTS-c: 200.9 142.25 mg dl 1 , exendin-4: 127.9 16.82 mg dl 1 , exendin-4 + MOTS-c: 134.5 14.085 mg dl 1 ) and delayed the onset of diabetes at 18 weeks of age (Fig

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Increased Satiety from Smaller Meals Protein and healthy fats digest more slowly than refined carbohydrates

This modality is based on the use of nanoparticles, with various size ranging from nanometre to micrometre scale based on a patented technology process