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The study was conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards

GLP-1RA use was associated with a reduction in depression, suggesting that GLP-1RA could potentially be considered an antidepressant therapy

4-weeks of 6-gingerol treatment increased glucose tolerance and glucose-stimulated insulin production

This becomes particularly important since inflammation in people with obesity may reduce blood-brain barrier integrity 28

The drugs also seemed to have a reno-protective effect, reducing the composite kidney outcome by 17%

Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs