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[45] [1] [46] According to a review done by the Canadian Medical Association, [1] there is an increase in the number of potential drugs that can interact with grapefruit juice, and of the number of fruit types that can interact with those drugs

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However, tirzepatide can cause dehydration through gastrointestinal fluid losses, particularly if patients experience significant nausea, vomiting, or diarrhea

Holst and colleagues in Denmark and by Joel Habener s group in the U.S., among others, who together elucidated the sequence and functions of GLP-1 in the mid-1980s ( [37] ) ( [38] )