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Weight management itself influences GLP-1 function

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GLP-1 medications like semaglutide work by reducing appetite and improving glucose control, leading to weight loss that may secondarily improve hormonal balance

A biweekly injection of a fatty-acylated version of this dual agonist improved body weight, glucose homeostasis and lipid metabolism in DIO mice [91]

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We used the same methodology to investigate the connection between GLP-1 agonism and the brains reward pathways to elucidate whether a connection exists between GLP-1 agonism and sexual desire