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Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial

For patients with PCOS, long-term treatment offers additional benefits

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adjusted HR (HRadj), 3.89

Studies show that GLP-1 doesnt just stimulate insulin, but it also slows digestion and changes how your pancreas responds to food

It should explain why semaglutide is medically necessary for your specific case, reference your diagnosis codes and comorbidities, cite the clinical trial evidence (STEP 1 showed 14.9% mean weight loss, NEJM 2021