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Revisiting Insulin Resistance in the Pathophysiology of Type 2 Diabetes Mellitus: A Multi-Organ Perspective, Diabetes & Metabolism Journal, 50 , 4, (641-665), (2026)

Lean mass as with any weight-loss intervention, some lean mass was lost

Reducing White Matter Injury Research shows that GLP-1 agonists safeguard oligodendrocytes as they decrease white matter hyperintensities in preclinical studies thus maintaining neural connections [13]

doi:10.2337/db09-0626 257

This liver-centric mechanism explains why both compounds dramatically reduce hepatic fat content

Tell your health care provider if you have any other medical conditions, including if you: Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and other medicines to treat diabetes, including insulin or sulfonylureas