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Patients may also have a harder time losing weight if they are on certain medications at the same time as a GLP-1 that can promote weight gain, such as certain antidepressants and beta blockers, Glickman says

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Its important that while on it encourage lifestyle modifications like exercise and proper diet Remove the drug, remove the effect, essentially

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GLP-3 exhibited a clear dose-dependent reduction in HbA1c, with the highest dose (12 mg) achieving a mean HbA1c reduction of 2.16 percentage points from baseline, compared to only 0.43% in the placebo groupan effect that was statistically highly significant

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Monthly check-ins Every 4 weeks, assess whether your current frequency and dose are optimal

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doi: 10.1016/s0026-0495(97)90170-0

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Bayesian updating can then incorporate emerging RCT and cohort evidence, revising effect estimates and widening or narrowing credible intervals as the evidence base evolves

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