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At this stage, the primary goal is not necessarily significant weight loss

In a study of two psoriasis patients with diabetes, liraglutide therapy for 6 weeks resulted in rapid clinical improvement, characterized by increased circulating i NKT cells and they also demonstrated in vitro that GLP-1 induced a dose-dependent reduction of cytokine secretion from i NKT cells [77]

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In some of these clinical studies, liraglutide treatment had been used for up to 52 weeks at doses ranging up to 3 mg daily (only in nondiabetic obese populations) or up to 1.8 mg daily (patients with type 2 diabetes) with no systematic change in calcitonin concentrations indicating any measurable response to GLP-1 receptor stimulation (34)

By Gabriel Alizaidy, MD, MS, and Starling Krentz, MS What are GLP-1 medications