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Further mechanism experiments revealed that dapagliflozin mitigated pro-inflammatory cytokines, nitro-oxidative stress, and fibrosis, as well as reduced apoptosis, and restored autophagy via activating adenosine monophosphate kinase (AMPK) and mTOR pathway [63]

doi: 10.1016/j.apsb.2024.03.011 [DOI] [PMC free article] [PubMed] [Google Scholar] 105.Apperloo EM, Neuen BL, Fletcher RA, et al