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Most side effects resolve within 24 weeks as your body adapts

FDA-Approved Alternatives Acamprosate [15] Second-line option Similar NNT to naltrexone (approximately 11) Major drawback: Requires 6-9 tablets daily High pill burden significantly impacts adherence More complex dosing for busy ED implementation Safe for patients with liver disease and opioid use disorder Disulfiram [18-21] Works as aversive agent, causing disulfiram reaction from accumulation of acetaldehyde, when combined with alcohol Recent RCTs show no significant benefit for reducing alcohol use Poor adherence due to fear of severe side effects Less likely to be prescribed in the ED, as naltrexone is a better option

Steven Swengel Board-Certified Dermatologist Since establishing RefinedMD in 2012, Dr

doi:10.1016/S0140-6736(21)00213-5

It plays a central role in appetite regulation, blood sugar control, and digestive timing

Nutrient Density Superfoods are rich in: Antioxidants : Protect joints from oxidative stress