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The most frequent adverse effects include gastrointestinal symptoms, appetite loss, tachycardia, pancreatitis, and a possible risk of thyroid tumors, warranting careful monitoring 21,22,23,24

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However, the renoprotective effects on renal function and histopathology were markedly attenuated in the ABX-db/db-T group versus db/db-T group (Figures 3BE)

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