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Clinical trial data show that while fat mass accounts for the majority of weight loss, some lean mass reduction also occurs, which could potentially affect muscle function

19 In a 68-week follow-up study, semaglutide 2.4 mg demonstrated a 9.7-kg weight loss versus 3.5 kg with lifestyle interventions alone

447 CETP inhibition, therefore, has the potential to reduce LDL-C while increasing HDL-C, a dual benefit in the context of ASCVD prevention

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