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It was the aim of this study to evaluate the potential of reverse micelles (RM) and hydrophobic ion pairs (HIP) for incorporation of semaglutide into self-emulsifying oral drug delivery systems

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The confirmatory secondary endpoint was change in body weight (kg) from baseline to week 26

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While side effects are often cited as a reason for GLP-1 non-adherence, the gap in persistence for the same molecule reflects deeper behavioral and systemic challenges