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For patients taking semaglutide, its particularly important to communicate with their healthcare provider to modify the medication regimen if needed

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Follow-up care allows the provider to adjust dosing, monitor progress, and address nutrition or hydration concerns

But the mechanistic rationale is sound, since the NF-kB and cytokine pathways that GLP-1 modulates are directly involved in Hashimoto pathogenesis

Long-term cost considerations also favor semaglutide for many patients

Semaglutide enhances insulin sensitivity and reduces blood sugar demand, while insulin provides direct glucose-lowering power