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However, lifestyle changes complement the drugs effects

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5.5 Heart Rate Increase Mean increases in resting heart rate of 2 to 3 beats per minute (bpm) were observed with routine clinical monitoring in SAXENDA-treated adult patients compared to placebo in clinical trials

Nunn E, Jaiswal N, Gavin M, Uehara K, Stefkovich M, Drareni K, Calhoun R, Lee M, Holman CD, Baur JA, Seale P, Titchenell PM

However, in circumstances where affordability and availability are important issues, it is still clinically useful to know which of the widely used and less-expensive medications, including SUs, can achieve glycemic targets with a low risk of adverse outcomes