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doi: 10.1016/j.molmet.2020.101102 [DOI] [PMC free article] [PubMed] [Google Scholar] 15.Perez-Montes DE, Oca A, Pellitero S, Puig-Domingo M

Testing the effects of the GLP-1 receptor agonist Exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder

Because it provides a constant level of insulin regardless of blood sugar status, blood glucose can drop dangerously low if a patient skips meals, exercises vigorously, or takes too much insulin

Key substrates are phosphorylated by PKA, which are involved in insulin synthesis and secretion [31]

Why Switch

continue increasing competition by introducing oral GLP-1, dual incretin and novel metabolic drugs