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Common GLP-1 medications include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)

It's especially beneficial for diabetic patients who may already be at risk for peripheral neuropathy

Results announced in October 2025 demonstrated orforglipron's superiority on both HbA1c and weight endpoints, positioning it as a more effective second-line oral agent than existing oral diabetes medications

We have shifted from a purely glucocentric approach to a beta cell-centric approach, emphasizing the importance of beta cell preservation and treatment durability

This starting dose is not therapeutically effective on its own it is a dose titration period to help the body adjust and reduce gastrointestinal side effects before escalating.

The difference lies in whether protective strategies are in place to safeguard mental well-being