glp-1 sglt2 inhibitors and receptor agonists: a sound combination GLP-1 receptor agonists and SGLT2

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[DOI] [PubMed] [Google Scholar] 108.Gerstein HC, et al

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

Its not clear if there is something unique about this class of drugs that leads to specific outcomes on the muscle, whether its a loss of mass or an improvement in muscle function and performance

'On top of that, improved metabolic health - especially in men with diabetes - can enhance blood flow and lead to firmer, more robust erections, which can look and feel larger.' Combined annual sales for Ozempic, Rybelsus and Wegovy He added: 'Finally, consider that men just want bigger penises, and they may just be seeing what they want to see.' Research shows that the average size of an erect penis in the US has increased by about 24 percent over the past 29 years, from an average of 4.8 inches to 6 inches

Instead, clinicians should acknowledge this risk and consider individualized risk-benefit strategies when prescribing GLP-1 RAs, particularly for patients with pre-existing ocular manifestations and must inform patients regarding possible ocular hazards while advocating for regular retinal examinations and assessments of visual acuity