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Leptin as a metabolic link to multiple sclerosis

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Fatigue is one of the first signs of dehydration

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In fact, extensive cardiovascular outcome trials have demonstrated that several GLP-1 agonists provide cardiovascular benefits rather than harm

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GLP-1 receptors are expressed in mood regulation brain regions, including the amygdala, hippocampus, prefrontal cortex, ventral tegmental area (VTA), and nucleus accumbens (NAc), where signaling modulates monoaminergic neurotransmission and hypothalamicpituitaryadrenal axis function [197,198]

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