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Description
Leptin as a metabolic link to multiple sclerosis
GLP-1-based therapies for diabetes contribute to reduce inflammation and have additional beneficial effects such as islet preservation and improvement of insulin sensitivity in addition to glucose-lowering effects

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In fact, extensive cardiovascular outcome trials have demonstrated that several GLP-1 agonists provide cardiovascular benefits rather than harm
GLP-1 receptors are expressed in mood regulation brain regions, including the amygdala, hippocampus, prefrontal cortex, ventral tegmental area (VTA), and nucleus accumbens (NAc), where signaling modulates monoaminergic neurotransmission and hypothalamicpituitaryadrenal axis function [197,198]

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