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Most patients report reduced food cravings, diminished portion sizes at meals, and decreased snacking urges within the first 37 days
Drug Interactions The concomitant use of JANUMET with specific drugs may increase the risk of metformin-associated lactic acidosis: those that impair renal function, result in significant hemodynamic change, interfere with acid-base balance or increase metformin accumulation [see Drug Interactions (7)]
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Lancet 2017;390:1664-75.ArticlePubMedPMC 83
Headaches Seven studies were identified concerning headache, migraine, and idiopathic intracranial hypertension (IIH) [23,24,25,26,27,28,29]
