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PL: Writing review & editing, Funding acquisition, Supervision

Clinicians should explain that evidence linking GLP-1 therapies to skin changes is still emerging

Currently, there are 20 oligonucleotide drugs approved by the FDA and the European Medicines Agency (EMA) and a majority of them treat orphan and rare diseases.In 2023, FDA approved four ONTs AstraZeneca-Ionis Wainua (eplontersen), Novo Nordisk owned Dicerna Pharmaceuticals Rivfloza (nedosiran), Biogen-Ionis Qalsody (tofersen) and Iveric Bios Izervay (avacincaptad pegol).In 2021, the global ONT market size was estimated to be US$ 18.2 billion

Enteroendocrine cells in terminal ileal Crohns disease

The clinical evidence shows that restarting GLP-1 medications after a break produces similar weight loss results as the initial treatment

Strengthens gut health for overall wellness and immune support