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Description
Yesafter discontinuing semaglutide, the effects wear off, often leading to weight regain
Isolated rat islets stimulated by GLP-1 have anti-diabetic effects through the activation of GLP-1 receptor agonists [29]
What Is GLP-1 Fatigue
Compare that to Tresiba, which typically causes weight gain of 1 to 4 kg over the treatment period
Scheme 6
Despite these promising early findings, both studies have limitations, including the single-center design, modest sample size, short follow-up in SKIP, reliance on self-reported outcomes, and lack of multicenter validation
