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[DOI] [PubMed] [Google Scholar] 34.Mosenzon O., Blicher T.M., Rosenlund S., Eriksson J.W., Heller S., Hels O.H., Pratley R., Sathyapalan T., Desouza C., PIONEER 5 Investigators Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): A placebo-controlled, randomised, phase 3a trial

It acts through a different pathway the ghrelin receptor amplifying the GH pulse and making the pituitary more responsive to GHRH signals

Circulation 138, 24862498
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Hypotension and orthostatic hypotension were more frequently seen in patients on concomitant antihypertensive therapy
