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And people gain the weight back when they come off it. Costs for five of the GLP-1 drugs Ozempic, Mounjaro, Wegovy, Zepbound, and Saxenda topped $300 million for Boston-based Blue Cross last year, more than double what it spent in 2023

The syndrome predisposes patients to endocrine tumors, particularly involving the thyroid

According to a 2019 review , GLP-1 and glucagon both play key roles in regulating thermogenesis and energy balance, suggesting that these hormones dont just influence appetite, but also how much heat your body produces at rest

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Some individuals lost up to 24% of their body weight when combined with proper diet and exercise