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In experimental models for the induction of tissue damage, 20 mg/kg MTX was a commonly used dose for rats (Reference Moodi, Hosseini and Abedini16Reference Azadnasab, Kalantar and Khorsandi20)
An in vitro study suggested that necroptosis is involved in the pathogenesis of PD through excitotoxicity, the accumulation of intracellular Ca 2+ or TNF, although its contribution to PD pathology is uncertain (Beal, 2008
K.FodemC.NguemoF.et al (2021)
The significance of ultraviolet radiation for eye diseases
Woodcock T, Morganti-Kossmann MC
After the reduction, a second alkylation step was carried out by adding 5 l of 100 mM d5-NEM
