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Neurotransmitter Synthesis B12 enables creation of feel good chemicals for mood like serotonin, dopamine, and norepinephrine

Barrier Disruption by Specific Microbes Intestinal pathobionts are often overrepresented in the microbiota of patients with inflammatory disorders, where they accelerate systemic inflammation by translocating across the epithelial barrier to reach extraintestinal tissue ( Figure 1 )

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