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The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation. Growth Hormone and IGF Research

doi:10.3390/medicina59050985 Chandrakumar H, Khatun N, Gupta T, GrahamHill S, Zhyvotovska A, McFarlane SI

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Stefano GB

Notably, excessive ROS can further exacerbate calcium homeostasis disorders by damaging the sarcoplasmic reticulum Ca-ATPase and mitochondrial calcium uniporter, forming a malignant cascade of excessive ROS-calcium imbalance-energy crisis [136]

Se is an enzymatic antioxidant that has no antioxidant effect by itself but participates in selenoproteins as redox-active selenoenzymes to safeguard against oxidative damage (172, 173)