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Hepsin/ mice exhibit exacerbated APAP toxicity, resulting in more severe liver damage, elevated oxidative stress, and higher mortality

Nonetheless, neurons seem to be uniquely constrained in their metabolic flexibility, with evidence indicating that they are unable to increase their glycolytic rate during intense neuronal activity (Chuquet et al

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A-T progressively manifests in multiple phenotypes, including immunodeficiency, neurological defects, cancer, telangiectasia, and diabetes without any established treatment 2

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