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Studies with tricyclic imide-based PROTACs targeting the hepatitis C virus (HCV) protease and the fibroblast growth factor receptor showed a higher affinity of these alternative ligands to cereblon compared to pomalidomide and lenalidomide 58,162

Acknowledgments The author, JR, gratefully acknowledges UPES, Dehradun, for offering the fellowship and providing the necessary infrastructure that contributed to the success of her doctoral research

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Application Protocol Summary Topical Application Notes Absorption timing: Published protocols describe application to clean, dry skin with 10-15 minutes of absorption time before layering other skincare products