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Important mechanisms of metabolic regulation, including CAR-T cell metabolic status reprogramming to meet the needs for both energy and biosynthesis during rapid expansion, and how these mechanisms balance divergent metabolic pathways to direct the formation of long-lived T M or short-lived T E cells are worthy of further investigation

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doi: 10.1016/j.jtcvs.2013.09.060

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13, 16 Second, the solubility of molecular oxygen is 700% higher within nonpolar than aqueous milieus (the hydrophobic regions of the membrane are generally the most nonpolar regions of the cell)