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doi: 10.1152/jappl.1999.86.1.195
Two biomarkers were selected for further analysis: adenylsuccinic acid and fumaric acid
Volkow ND, Fowler JS, Wang GJ, Ding YS, Gatley SJ
Knockdown of PAX-interacting protein 1 ( PAXIP1 ) or nucleosome remodeling factor CHD4 restored cisplatin resistance in BRCA2 -deficient B lymphocytes and an ovarian cancer cell line via inhibition of recruitment of MRE11A and diminished degradation of replication forks, independent of HR [27, 28]
A highly efficacious oral agent that can be used for both induction and maintenance therapy would be a major breakthrough for UC patients (Table 4)
Depletion of intracellular GSH is a hallmark of ferroptosis, as it impairs antioxidant defenses
