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A decrease in reduced and an increase in oxidized GSH was shown in the brain on rat models of temporary global and focal cerebral ischemia [14, 15]

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and Zhang H., Targeting Oxidative Stress in Disease: Promise and Limitations of Antioxidant Therapy, Nature Reviews Drug Discovery 20, no

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[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Hagen T.M., Ingersoll R.T., Lykkesfeldt J., Liu J., Wehr C.M., Vinarsky V., Bartholomew J.C., Ames A.B