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ROS also attack unsaturated fatty acids in cell membranes and lipoproteins, triggering lipid peroxidation that compromises membrane integrity and fluidity [109]
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Given that the transcription factor ATF3 induces P21 CIP expression while high c-Jun activity represses P53-mediated P21 CIP induction, 38, 39 the precise c-Jun/ATF2 and ERK1/2 activations regulate the transient increase in p21 CIP protein amounts required to stabilize CyclinD/CDK4/6 complexes from 36 to 40 h in WT mice
A CNT is a tube made of carbon atoms organized in a series of condensed benzene rings with a diameter in the nanometer range that can penetrate BBB [196]
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doi: 10.1038/bjp.2008.153
