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This mixture was incubated at 25 C for 20 min

Yes, they can

Progress and future directions with peptide-drug conjugates for targeted cancer therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Gong J., Osipov A., Lorber J., Tighiouart M., Kwan A.K., Muranaka H., Akinsola R., Billet S., Levi A., Abbas A., et al

The short answer here is yes
