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Wu Z, Kim ER, Sun H, Xu Y, Mangieri LR, Li DP, et al

Individuals with a history of depression, anxiety disorders, bipolar disorder, or previous suicidal thoughts or attempts should be carefully evaluated before initiating therapy

Weight reduction is likely mediated by delayed gastric emptying, enhanced satiety, and reduced caloric intake 16

This schedule uses the largest practical dilution (3.0 mL) to maintain perinjection accuracy

In addition, the enteric nervous system (ENS), which is a recognized second brain that can regulate many GI functions independent of CNS action, can also act as an intermediate in relaying gut-derived information to the CNS 25

O'Dell JR