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Higher-risk groups include the following: Older adults Vegetarians and vegans People with digestive disorders Individuals taking certain medications Those recovering from gastrointestinal surgery Pregnancy and vitamin B12 deficiency can also require careful monitoring, as adequate vitamin B12 levels are important for both maternal and foetal health

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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Kasimatis G, Fitz-Gibbon S, Tomida S, Wong M, Li H, Analysis of complete genomes of Propionibacterium acnes reveals a novel plasmid and increased pseudogenes in an acne associated strain

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Less threatening reaction to B1 include anxiety, pruritus, respiratory distress, nausea, abdominal pain

Do not exceed what they advise, and complete the full treatment, as stopping early can result in a recurrence or worsening of the problem