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Interestingly, this stress response was not observed in a liver-specific CoQ deficiency animal strain (PDSS2 AlbKO ) (Appendix Fig

It is important to acknowledge a significant limitation in the current evidence base

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Lipoyl (octanoyl) transferase 2 catalyzes the transfer of the octanoyl moiety from ACP to a conserved lysine in the H protein of the glycine cleavage complex (see Biological Activities and Figure 3)