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Several studies have investigated the impact of lifestyle factors, such as smoking, on defecation habits, which can cause both constipation and diarrhea [51, 52]

This suggests that overexpression of GLT-1 on spinal cord astrocytes attenuates the induction, but not the maintenance, of inflammatory pain and NP

Our recent study demonstrated that stimulation of astrocytic 5-HT1A receptors promoted astrocyte proliferation and upregulated antioxidative property in astrocytes to protect dopaminergic neurons against oxidative stress

When Srx1 was deleted and tested in in addition to the peroxiredoxins TSA1 and TSA2, which are localized in the cytoplasm, these proteins were found to be induced in the presence of neutrophils, required for survival in these phagocytic cells, and implicated in the oxidative stress response (ROS)

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Epigenetic deregulation contributes to its pathogenesis by promoting a proinflammatory phenotype in peripheral immune cells
