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Experimental Dermatology, 28 (3), 219-224

12:10 Hrs

The peptide has shown a generally favorable safety profile, with most adverse events being mild and transient

Studies in hyperammonemic rat models revealed that SFN promotes microglia differentiation from pro-inflammatory M1 to anti-inflammatory M2 phenotypes, mitigating neuroinflammation [35]

Chiu-Ugalde J, Wirth EK, Klein MO, Sapin R, Fradejas-Villar N, Renko K, et al

Whole-cell lysates were separated by SDS-PAGE, transferred to a PVDF membrane (Millipore, Shanghai, China), and blocked with 5% non-fat dry milk in Tris-buffered saline with 0.1% Tween 20 (TBST)