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NK cells, in particular, show a marked and sustained decrease in surface CD38 following antibody treatment

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Those with specific nutritional deficiencies, athletes, or anyone experiencing fatigue and stress can benefit from this treatment

In diet-induced obesity (DIO) models, NNMT loss-of-function and selective small-molecule inhibitors reduce white adipose mass and improve metabolic parameters without overt toxicity, positioning NNMT as a tractable target for metabolic-disease research [24]