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Firstly, AI has guided the design of LNPs with two novel ionizable lipids, including FO32 and FO35, screened from a million lipids in silico, which show better pulmonary mRNA delivery than previously reported lipids [190]

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The highest plasma concentrations of NAC were detected up to 1 h following oral administration with the terminal t 1/2 of about 6 h [22, 23]

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