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Mutations of key enzymes of the TCA cycle in TC By producing reducing equivalents in NADH and FADH 2 , mitochondria oxidate substrates through the TCA cycle, not only catabolizing bioenergy fuels, but also providing precursors for other anabolic processes [183]

Studies on cyclists show nitrate supplementation lowers submaximal VO2 by 5% while maintaining the same power output, meaning the work feels easier even when producing identical watts

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35 WuX.GaoY.ShiC.TongJ.MaD.ShenJ.et al (2023)

doi: 10.1016/j.biopha.2019.109249

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