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The most advanced of the prodrug candidates is TLK286, -glutamyl- -amino- -(2-ethyl- N , N , N , N -tet-rakis (2-chloroethyl) phosphorodiamidate)-sulfonyl-propionyl-( R )-() phenylglycine)

Vitamin B12, also known as cobalamin, is an essential nutrient that plays several vital roles in the body

Furthermore, they demonstrated that chondrocyte lipid peroxidation contributed to the oxidation and degradation of collagen, which in turn may aggravate OA by increasing the sensibility of cartilage to mechanical fatigue [51]

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Here, we investigate the relationship between repair of each of the two strand breaks of a DSB during repair by NHEJ, as well as the importance of the end-bridging complex in directing each strands repair