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In a C57BL/6J mouse model of AD, apigenin significantly upregulated the expression of CAMP and mouse -defensin 3 (mBD3), which may contribute to increased local antimicrobial activity (Hou et al., 2013)

[DOI] [PMC free article] [PubMed] [Google Scholar] 317

[DOI] [PubMed] [Google Scholar] 147.Berk M., Munib A., Dean O., Malhi G.S., Kohlmann K., Schapkaitz I., Jeavons S., Katz F., Anderson-Hunt M., Conus P., Hanna B., Otmar R., Ng F., Copolov D.L., Bush A.I

While this protein was an interesting target warranting further investigation, given the smaller sample size and duration post sample collection, we sought to determine if these findings were replicable in a larger and more recent study cohort

Although not as well-known as weight-loss peptides like GLP-1s like semaglutide and tirzepatide, 5-Amino-1MQ is becoming one of the most talked-about compounds in functional medicine for its similar role in weight loss and metabolic support