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Correlating this finding, ncr-1 and ncr-2 double mutants present a constitutive dauer formation (Daf-c) phenotype [116]

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Debido a su magnitud y trascendencia, la obesidad es considerada en Mxico como un problema de Salud Pblica, como lo demuestra lo reportado por la Encuesta Nacional de Salud del ao 2000, detectando que desde edades tempranas existe una elevada prevalencia de sobrepeso y obesidad, ya que en los adolescentes se encuentra un 29% de sobrepeso y obesidad y, en lo referente a los adultos, en mujeres de 20-59 aos se obtuvo un 36.1% de sobrepeso y 28.1% de obesidad y, en hombres del mismo grupo, 40.9% de sobrepeso y 18.6% de obesidad

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Moreover, the thick cuticle of the skin and the presence of proteases and the acidic pH in the gut of the worms make it extremely difficult to administer proteins in this animal model, thus limiting its use for the discovery of potential protein-based therapeutics

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CEBPB further promotes EMT by inducing nuclear translocation of NF-B, reducing E-cadherin expression, and elevating vimentin and tenascin levels, thereby enhancing RCC cell motility [88]

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Energy intake and amyotrophic lateral sclerosis

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