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Medical supervision is required
Exercise itself induces MOTS-c production in human skeletal muscle

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Another rare risk is hypokalemia (low potassium), with symptoms like muscle weakness and irregular heartbeat, which can occur when treatment begins for severe anemia

[DOI] [PMC free article] [PubMed] [Google Scholar] Elia 1998 Elia M
[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Widstrm AM, Winberg J, Werner S, Hamberger B, Eneroth P, Uvns-Moberg K
