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The most common error involves vigorous shaking during reconstitution, which denatures the peptide structure and renders it inactive

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Almeida RC, Souza DG, Soletti RC, Lpez MG, Rodrigues AL, Gabilan NH (2006) Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice