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J Clin Endocrinol Metab 105(11) 2020 PMC7500476 Wang K, Nguyen M, Chen Y, Hoofnagle AN, Becker JO, Zelnick LR, Kundzins J, Goodling A, Himmelfarb J, Kestenbaum B

7.4 Alkaloids: suppressors of apoptosis and metabolic dysfunction Alkaloids attenuate ALD by suppressing the MAPK/NF-B axis, thereby reducing ERK/JNK phosphorylation and TNF- production, which mitigates hepatocyte apoptosis ( Oxymatrine, a quinolizidine alkaloid from the roots of Sophora flavescens Aiton [Fabaceae], inhibits ERK1/2-mediated apoptosis and downregulates pro-inflammatory cytokines ( Berberine, an isoquinoline alkaloid from traditional Chinese medicinal herbs such as Coptis chinensis Franch

THC, the active compound in cannabis, has been shown to alter sperm morphology, impair sperm motility, and affect the acrosome reaction needed for fertilisation

L-Carnitine for Depression Depression is a complex mental health condition influenced by various factors, including neurotransmitter imbalances, inflammation, oxidative stress, and genes

PG is suggested to play a critical role in the cytotoxic and potentially carcinogenic effects of gallate (Additives et al

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