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Interestingly, in anxiety disorders, there is increased expression of GLO I, coupled with a reduction in MG concentration in the brain

In contrast, patients with stiff-person syndrome predominantly recognize linear epitopes in all three domains on GAD65 and GAD67 (28), and specifically in the first 100aa, which constitute the regulatory sequence in the N-terminal GAD65 domain that is not recognized by the diabetes mellitus sera (61)

In recent years, a variety of non-histone proteins have also been shown to be methylated, such as P53 and AKT[184-186]

2012 ASCO Meeting, 2012

Their value is mechanical and structural